How Bold Cultures Drive Radical Innovation in Science-Led Companies


In a business world obsessed with disruption, it's tempting to think that innovation starts with big ideas or breakthrough technologies. But in science-led companies, where complexity, compliance, and rigor rule the day, innovation doesn't begin in a lab. It begins in the culture. 

In this episode of Advancing Ideas, Cultivate's Founder and CEO Steve Garguilo and Chief Innovation Officer Bhavik Modi break down the link between bold organizational cultures and sustainable innovation.

Spoiler: Culture isn’t just a support system for innovation. It’s the launchpad. 

Why Culture is the Real Innovation Engine

It’s a common mistake to think innovation is about hiring the right experts or implementing agile methodologies. These things matter, but they aren’t enough. As Steve Garguilo puts it: 

“Innovation doesn’t start with technology or ideas—it starts with culture.” 

Organizations that consistently deliver innovation have something in common: cultures that reward experimentation, de-risk failure, and elevate curiosity. In other words, they create a climate where people feel safe pushing boundaries. 

Especially in science-led organizations, where precision and predictability often dominate, the culture must be intentionally shaped to encourage innovation without compromising excellence.  

The Three Cultural Conditions Innovation Needs to Thrive

Psychological Safety  

When employees fear mistakes, they self-censor. Cultures that foster psychological safety enable idea-sharing, risk-taking, and faster iteration—all core ingredients for innovation. 

Permission to Experiment 

In high-performance organizations, “failure” often has negative consequences. But bold cultures recognize that experimentation is essential for progress, and they reward learning over perfection. 

Aligned Purpose and Curiosity

Innovation is strongest when people understand the “why”. Cultures that link everyday work to a meaningful purpose energize teams and unlock intrinsic motivation. 

What Bold Leaders Do Differently

Innovation doesn’t scale without leadership support. But support isn’t enough - leaders must model the culture they want to see. 

Bhavik Modi shares: 

“Leaders must go beyond driving results. They must create the conditions for others to experiment, challenge assumptions, and learn out loud.” 

In bold cultures, leaders: 

  • Ask better questions instead of always providing answers 

  • Celebrate progress, not just outcomes 

  • Make it safe to surface tensions, conflicts, or missteps 

From Culture Talk to Culture Work

At Cultivate, we believe that culture is built through behavior. It’s not a branding exercise. It’s what gets rewarded, reinforced, and repeated. That’s why science-led companies must evolve how they measure and manage culture—not as a side initiative, but as a strategic priority. 

We work with teams to identify: 

  • Moments where culture gets shaped (like onboarding, team rituals, and performance reviews) 

  • Opportunities to amplify the right behaviors 

  • Systems that make experimentation a sustainable practice 

The Innovation-Culture Flywheel

When innovation succeeds, it reinforces the behaviors that led to it. But this flywheel can also reverse: if innovation efforts fail in a punitive culture, risk aversion intensifies. 

 Bold cultures ensure the flywheel spins forward. They: 

  • Normalize iterative cycles 

  • Make room for reflection and learning 

  • Keep teams aligned on a shared purpose 

The Bottom Line

Radical innovation doesn’t live in strategy decks or innovation labs. It lives in everyday conversations, behaviors, and decisions. In science-led organizations, where excellence is non-negotiable, culture is the competitive advantage. 


Cultivate empowers organizations to not just adapt to change, but to lead in shaping the future of work. Let us help you build a thriving culture now — send us a message

Steve Garguilo

Steve is an instigator with a track record of large-scale, grassroots change. He previously led the revolution to transform the culture at Johnson & Johnson.

https://www.linkedin.com/in/sdgarguilo/
Previous
Previous

Building the Future of Work: Why Innovation Requires Rethinking Organizational Culture

Next
Next

We're a 2025 ATD BEST Award Winner — and Proud of It